GLP1 agonist (weight loss injections ) and oral HRT progesterons

If you have been prescribed weight loss injections whilst also using oral forms of progesterone for HRT.

New guidelines suggest that weight loss injections may delay the absorption of oral progesterones, which could lead to insufficient protection of the endometrium (womb lining) from oestrogen.

Please contact the practice for a review so that we can discuss potential alternatives (eg a non-oral progesterone or a dose change)

Published on 3 June 2025